Adoption of Gla-100 in India and its Impact on Insulin Usage Patterns.

Viswanathan Mohan, K D Modi, Sujeet Jha, Subodh Banzal, Biplab Bandopadhyay, G D Ramchandani, Sridevi Atluri, Radhika V Kumar, Sushil Kiran Kunder, Ranjit Unnikrishnan

Journal: The Journal of the Association of Physicians of India 2020;68(12[Special]):25-30

PMID: 33247660

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Abstract

Fueled by perceptions regarding Indian dietary patterns and premixed insulin's claim to fame of providing dual fasting and post-prandial control, there was a greater inclination towards using premixed insulins in clinical practice until the last decade. However, the advent of insulin glargine 100 U/mL (Gla-100) opened up a new dimension in insulin therapy landscape in India. The data from the last 5 years reveal that Gla-100 has gained more traction among Indian clinical practitioners. Basis evidences that have emerged from various clinical studies, this present review elaborates on certain key issues which have helped Gla-100 carve its own niche and effected a progressive shift in insulin prescription pattern in India.

Address: Senior Consultant, Department of endocrinology, CARE Hospitals, Hyderabad, Telangana.; Principal Director - Endocrinology, Diabetes and Obesity, Max Superspeciality Hospital, Delhi.; Senior Consultant, Diabetes and Hormones care, Indore, Madhya Pradesh.; Senior Consultant, Thyroid Diabetes and Hormone Care Clinic, Raipur, Chhattisgarh.; Consultant, Ramchandani Diabetes Care and Research Center, Kota, Rajasthan.; Consultant, Vydehi Hospital, Bangalore, Karnataka.; Consultant, Columbia Asia Hospital, Bangalore, Karnataka.; Medical Affairs, Diabetes and Cardiovascular, Sanofi India Ltd.; Director and Consultant Physician, Dr. Mohan's Diabetes Specialities Centre and Madras Diabetes Research Foundation, Chennai.; Chairman and Chief Diabetologist, Dr. Mohan's Diabetes Specialities Centre, Chennai, Tamil Nadu.

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https://medlineplus.gov/diabetestype2.html

MeSH Terms: Diabetes Mellitus, Type 2, Glycated Hemoglobin, Humans, Hypoglycemia, Hypoglycemic Agents, India, Insulin, Insulin Glargine, Insulins