Nudix proteins affecting microbial pathogenesis.

Elzbieta Kraszewska, Joanna Drabinska

Journal: Microbiology (Reading, England) 2021;166(12):1110-1114

PMID: 33253082

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Abstract

Nudix proteins catalyse hydrolysis of pyrophosphate bonds in a variety of substrates and are ubiquitous in all domains of life. Their widespread presence and broad substrate specificity suggest that they have important cellular functions. In this review, we summarize the state of knowledge on microbial Nudix proteins involved in pathogenesis.

Address: Institute of Biochemistry and Biophysics Polish Academy of Sciences, Pawinskiego 5A, 02-106, Warsaw, Poland.

DOI: 10.1099/mic.0.000993

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MeSH Terms: Amino Acid Sequence, Bacterial Proteins, Diphosphates, Pyrophosphatases, Sequence Alignment, Viral Proteins, Virulence, Virulence Factors, Nudix Hydrolases