Therapeutic Options for the Treatment of Coronavirus Disease (COVID-19).

Jessica Snawerdt, Lauren Finoli, Derek N Bremmer, Tariq Cheema, Nitin Bhanot

Journal: Critical care nursing quarterly 2020;43(4):349-368

PMID: 32833772

Abstract

Coronavirus disease 2019 (COVID-19) has resulted in an unprecedented pandemic, challenging practitioners to identify safe and effective therapeutic options in a limited amount of time. The rapid genomic sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provided a significant number of therapeutic targets. Repurposed and investigational agents are being studied for use in COVID-19. Although knowledge is rapidly expanding in regard to COVID-19 and there is promise with a few agents, there are no definitely proven effective therapies at this time. Supportive care remains the mainstay of therapy while ongoing clinical trials are being conducted.

Address: Department of Pharmacy (Drs Snawerdt, Finoli, and Bremmer), Division of Pulmonary Critical Care (Dr Cheema), and Division of Infectious Disease (Dr Bhanot) Allegheny General Hospital, Allegheny Health Network, Pittsburgh, Pennsylvania.

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