Vicia plants-A comprehensive review on chemical composition and phytopharmacology.

Bahare Salehi, Ibrahim M Abu-Reidah, Farukh Sharopov, Natallia Karazhan, Javad Sharifi-Rad, Muhammad Akram, Muhammad Daniyal, Fahad Said Khan, Wafa Abbaass, Rida Zainab, Katya Carbone, Nouran M Fahmy, Eman Al-Sayed, Mohamed El-Shazly, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Miquel Martorell, Raffaele Pezzani

Journal: Phytotherapy research : PTR 2021;35(2):790-809

PMID: 32930444

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Abstract

The plants belonging to the genus Vicia are of great interest as a source of many bioactive compounds and micronutrients. A snapshot of their cultivation, habitat, main components, from which essential oils can be obtained, is given. The traditional medicinal uses of Vicia plants are also reported, as well as the wide spectrum of the main biological activities attributed to Vicia plants is discussed regarding potential health beneficial properties, in particular anti-Parkinson, anticholinesterase, antidepressant, anticonvulsant, antimicrobial, cytotoxic, antioxidant, antiinflammatory and antinociceptive, antidiabetic, antihemolytic, anticoagulant, estrogenic, diuretic, antihypoxic activities.

Address: Noncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran, Bam, Iran.; Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran.; Department of Environmental Science/Boreal Ecosystem Research Initiative, Memorial University of Newfoundland, Corner Brook, Newfoundland and Labrador, Canada.; Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.; Department of Pharmacognosy, Pharmaceutical Faculty of the EE VSMU, Vitebsk, Republic of Belarus.; Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Department of Eastern Medicine, Government College University Faisalabad, Faisalabad, Pakistan.; TCM and Ethnomedicine Innovation & Development International Laboratory, Innovative Drug Research Institute, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China.; Department of Eastern Medicine, University of Poonch, Rawalakot, Pakistan.; CREA, Research Centre for Olive, Citrus and Tree Fruit, Rome, Italy.; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Cairo, Egypt.; Department of Pharmaceutical Biology, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, Egypt.; CREA-Research Centre for Food and Nutrition, Rome, Italy.; Department of Pharmacy, University of Napoli Federico II, Naples, Italy.; Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion, Chile.; Universidad de Concepción, Unidad de Desarrollo Tecnológico, UDT, Concepcion, Chile.; Department of Medicine (DIMED), OU Endocrinology, University of Padova, Padova, Italy.; AIROB, Associazione Italiana per la Ricerca Oncologica di Base, Padova, Italy.

DOI: 10.1002/ptr.6863

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MeSH Terms: Antioxidants, Humans, Plant Extracts, Vicia