A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean.

Cecilia Anza-Ramírez, Antonio Bernabé-Ortiz, Rodrigo M Carrillo-Larco, C Joel Benites-Moya, Leonardo Albitres-Flores, Diana Sánchez-Velazco, Niels Pacheco-Barrios

Journal: eLife 2021;9():e57980

PMID: 32807300

Abstract

We aimed to study time trends and levels of mean total cholesterol and lipid fractions, and dyslipidaemias prevalence in Latin America and the Caribbean (LAC). Systematic-review and meta-analysis of population-based studies in which lipid (total cholesterol [TC; 86 studies; 168,553 people], HDL-Cholesterol [HDL-C; 84 studies; 121,282 people], LDL-Cholesterol [LDL-C; 61 studies; 86,854 people], and triglycerides [TG; 84 studies; 121,009 people]) levels and prevalences were laboratory-based. We used Scopus, LILACS, Embase, Medline and Global Health; studies were from 1964 to 2016. Pooled means and prevalences were estimated for lipid biomarkers from ≥2005. The pooled means (mg/dl) were 193 for TC, 120 for LDL-C, 47 for HDL-C, and 139 for TG; no strong trends. The pooled prevalence estimates were 21% for high TC, 20% for high LDL-C, 48% for low HDL-C, and 21% for high TG; no strong trends. These results may help strengthen programs for dyslipidaemias prevention/management in LAC.

© 2020, Carrillo-Larco et al.

Address: Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.; Universidad Católica Los Ángeles de Chimbote, Instituto de Investigación, Chimbote, Peru.; Facultad de Medicina de la Universidad Nacional de Trujillo, Trujillo, Peru.; Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo-SOCEMUNT, Trujillo, Peru.; Universidad Científica del Sur, Lima, Peru.
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