RENISUS Plants and Their Potential Antitumor Effects in Clinical Trials and Registered Patents.

Diorge Jônatas Marmitt, Shanna Bitencourt, Gustavo Rodrigo da Silva, Claudete Rempel, Márcia Inês Goettert

Journal: Nutrition and cancer 2021;73(10):1821-1848

PMID: 32835511

Abstract

Cancer is a significant cause of morbidity and mortality. Scientific advances, coupled with potential flaws in current treatments, are driving research into the discovery of new bioactive molecules. This systematic review focused on scientific studies with clinical trials and patents registered on the National Relation of Medicinal Plants of Interest to the Unified Health System (RENISUS) plants (or derivative compounds) with antitumor potential. Studies with 19 different forms of cancer were found, the prostate being the organ with the highest research incidence and the species , , and , beside the phytochemicals curcumin and soy isoflavone were the most tested in clinical trials/patents.

Address: Laboratório de Cultura de Células, Programa de Pós-graduação em Biotecnologia, Universidade do Vale do Taquari (Univates), Lajeado, Brazil.; Centro de Ciências Biológicas e da Saúde, Universidade do Vale do Taquari (Univates), Lajeado, Brazil.; Programa de Pós-graduação em Ambiente e Desenvolvimento/Programa de Pós-graduação em Sistemas Ambientais Sustentáveis, Universidade do Vale do Taquari (Univates), Lajeado, Brazil.

DOI: 10.1080/01635581.2020.1810290

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https://www.tandfonline.com/doi/10.1080/01635581.2...

MeSH Terms: Zingiber officinale, Humans, Neoplasms, Phytochemicals, Phytotherapy, Plants, Medicinal