Chemical Constituents from Sargassum fusiforme (Harv.) Setch.

Si-Yu Wang, Jun Xiang, Xiao-Jun Huang, Xia Wei, Qi Zhang, Xian-Hua Du, Jin-Shan Hu, Yu-Mei Wang, Cui-Xian Zhang

Journal: Chemistry & biodiversity 2021;17(6):e2000182

PMID: 32298046

Abstract

Phytochemical investigation of Sargassum fusiforme (Harv.) Setch. led to the discovery of fifteen secondary metabolites, including three sterols, three monoterpenes, five nitrogenous compounds, two fatty acids, and two others. Among them, two compounds are new, while the other thirteen compounds were isolated from S. fusiforme for the first time. The structures of the two new compounds were identified by NMR and HR-ESI-MS data analyses, and the absolute configurations were established by comparing the calculated and experimental ECD spectroscopic data.

Address: School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, P. R. China.; Department of Pharmacy, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510120, P. R. China.; Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research, College of Pharmacy, Jinan University, Guangzhou, 510632, P. R. China.

DOI: 10.1002/cbdv.202000182

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https://doi.org/10.1002/cbdv.202000182

MeSH Terms: Circular Dichroism, Fatty Acids, Magnetic Resonance Spectroscopy, Molecular Conformation, Monoterpenes, Sargassum, Sterols