Jasmohan S Bajaj, Mette Lauridsen, Elliot B Tapper, Andres Duarte-Rojo, Robert S Rahimi, Puneeta Tandon, Debbie L Shawcross, Dominique Thabut, Radha K Dhiman, Manuel Romero-Gomez, Barjesh C Sharma, Sara Montagnese
Journal: The American journal of gastroenterology 2020;115(7):989-1002
PMID: 32618647
Management of hepatic encephalopathy (HE) remains challenging from a medical and psychosocial perspective. Members of the International Society for Hepatic Encephalopathy and Nitrogen Metabolism recognized 5 key unresolved questions in HE management focused on (i) driving, (ii) ammonia levels in clinical practice, (iii) testing strategies for covert or minimal HE, (iv) therapeutic options, and (v) nutrition and patient-reported outcomes. The consensus document addresses these topical issues with a succinct review of the literature and statements that critically evaluate the current science and practice, laying the groundwork for future investigations.
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