Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis.

Maria Angela Tosca, Roberta Olcese, Guido Marinelli, Maria Papale, Anna Maria Zicari, Gianluigi Marseglia, Giorgio Ciprandi

Journal: Acta bio-medica : Atenei Parmensis 2021;91(2):356-359

PMID: 32420973

Abstract

Antihistamines are the cornerstone treatment of allergic rhinitis (AR). To quantify the antihistaminic consume is particularly relevant in clinical practice, since a remarkable use is usually associated with severe symptoms. The aim of the study was to measure the use of antihistamines in two groups of children suffering from AR. The first group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). Both groups took antihistamines on demand. The children were visited at baseline and after 1 year. The number of days of antihistaminic use was the primary outcome. Children in AG had a significant reduced number of antihistamines use in comparison with CG (p=0.008). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the use of symptomatic antihistamines in children with allergic rhinoconjuncti- vitis.

Address: Allergy Center, Istituto Giannina Gaslini, Genoa, Italy. [email protected].; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy University . [email protected].; Pediatrics Department, Umberto I Hospital, Roma, Sapienza University , Roma, Italy. [email protected].; Department of Pediatrics, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. [email protected].; Allergy Clinic, Villa Montallegro, Genoa, Italy. [email protected].
Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.