Management of adrenal incidentalomas: Working through uncertainty.

Sophie Cambos, Antoine Tabarin

Journal: Best practice & research. Clinical endocrinology & metabolism 2021;34(3):101427

PMID: 32448594

Full Text on Elsevier Science View on PubMed

Abstract

The European society of endocrinology, in association with the European network for the study of adrenal tumors, published recommendations for the diagnosis and treatment of adrenal incidentalomas in 2016. A thorough and critical analysis of the literature was performed to establish evidence-based recommendations and expert suggestions with the aim of avoiding 'over-diagnosis' and 'over-treatment' and to reduce unnecessary investigations, surgery and follow-up. The purpose of this review is to reconsider several recommendations that are open to debate, such as imaging of adrenal incidentalomas, diagnosis of pheochromocytoma, diagnosis and treatment of autonomous cortisol-secreting tumors, investigations of bilateral AI and follow-up of non-operated AIs, based on studies published after the release of the recommendations.

Address: Department of Endocrinology, Diabetes and Nutrition, University Hospital of Bordeaux, 33604 Pessac, France.; Department of Endocrinology, Diabetes and Nutrition, University Hospital of Bordeaux, 33604 Pessac, France; Inserm U1215, Neurocentre Magendie, University of Bordeaux, 146 Rue Leo Saignat, 33076 Bordeaux Cedex, France. Electronic address: [email protected].

DOI: 10.1016/j.beem.2020.101427

Link outs

Free resources

Medical:

https://medlineplus.gov/adrenalglandcancer.html

Subscription / membership required

Full Text Sources:

MeSH Terms: Adrenal Gland Neoplasms, Diagnostic Imaging, Diagnostic Techniques, Endocrine, Endocrinology, Humans, Hydrocortisone, Incidental Findings, Uncertainty