Postoperative management of patients with pituitary tumors submitted to pituitary surgery. Experience of a Spanish Pituitary Tumor Center of Excellence.

M Araujo-Castro, E Pascual-Corrales, J S Martínez San Millan, G Rebolleda, H Pian, I Ruz-Caracuel, G De Los Santos Granados, L Ley Urzaiz, H F Escobar-Morreale, V Rodríguez Berrocal

Journal: Endocrine 2021;69(1):5-17

PMID: 32170587

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Abstract

There is a lack of evidence on timing, frequency, and duration of postoperative endocrine, radiologic, and ophthalmologic assessments that should be performed after pituitary surgery (PS). However, it is known that careful optimization of treatment and follow-up strategies as well as a multidisciplinary approach may have a significant impact on long-term outcomes, improving surgical results, minimize complications and facilitate their correct treatment if occurring, and optimize the hormonal, ophthalmological, and radiological reassessment throughout the follow-up. Considering that there are no specific guidelines on the postoperative management of patients with pituitary tumors (PT), we present our protocol for the postoperative management of patients with PT. It has been elaborated by the multidisciplinary team of a Spanish Pituitary Tumor Center of Excellence (PTCE) that includes at least one neurosurgeon, ENT, neuroradiologist, neuro-ophthalmologist, endocrine pathologist and endocrinologist specialized in pituitary diseases. We elaborated this guideline with the aim of sharing our experience with other centers involved in the management of PT thereby facilitating the postoperative management of patients submitted to PS.

Address: Neuroendocrinology Unit, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain. [email protected].; Hospital Universitario Ramón y Cajal, M-607, km. 9, 100, 28034, Madrid, Spain. [email protected].; Neuroendocrinology Unit, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Neuroradiology Unit, Department of Diagnostic Imaging, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Neuro-Ophthalmology Unit, Department of Ophthalmology, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Universidad de Alcalá, Madrid, Spain.; Endocrinology Unit, Department of Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Universidad de Alcalá, Madrid, Spain.; Rinology Unit, Department of Otorhinolaryngology (ENT), Hospital Universitario Ramón y Cajal, Madrid, Spain.; Instituto de Investigación Sanitaria Ramón y Cajal (IRYCIS), Madrid, Spain.; Pituitary Surgery Unit, Department of Neurosurgery, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Neuroendocrinology Unit, Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Universidad de Alcalá, Madrid, Spain.; Instituto de Investigación Sanitaria Ramón y Cajal (IRYCIS), Madrid, Spain.; Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, Spain.

DOI: 10.1007/s12020-020-02247-y