Computational approaches to unravel the pathways and evolution of specialized metabolism.

Marek Mutwil

Journal: Current opinion in plant biology 2020;55():38-46

PMID: 32200228

Full Text on Elsevier Science View on PubMed

Abstract

Specialized metabolites serve as a chemical arsenal that protects plants from abiotic stress, pathogens, and herbivores, and they are an essential component of our nutrition and medicine. Despite their importance, we are still at the beginning of unravelling biosynthetic pathways that produce these compounds, which is needed to produce more resilient and nutritious crops, expand our inventory of useful biomolecules, and give valuable insights into plant evolution. This review focuses on the evolution of specialized metabolism in the plant kingdom and the state-of-the-art approaches used to identify the biosynthetic pathways of these useful compounds.

Address: School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637551, Singapore. Electronic address: [email protected].

DOI: 10.1016/j.pbi.2020.01.007

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MeSH Terms: Crops, Agricultural