The potential health benefits of the isoflavone glycoside genistin.

Anowarul Islam, Md Sadikul Islam, Md Nazim Uddin, Mir Md Iqbal Hasan, Md Rashedunnabi Akanda

Journal: Archives of pharmacal research 2020;43(4):395-408

PMID: 32253713

Abstract

Genistin is a type of isoflavone glycoside and has a broad range of health benefits. It is found in a variety of dietary plants, such as soybean, kudzu (Japanese arrowroot), and other plant-based products. Genistin has been described to have several beneficial health impacts, such as decreasing the risk of osteoporosis and post-menopausal symptoms, as well as anti-cancer, anti-oxidative, cardioprotective, anti-apoptotic, neuroprotective, hepatoprotective, and anti-microbial activities. It may also assist individuals with metabolic syndrome. This review summarizes some of the molecular impacts and prospective roles of genistin in maintaining and treatment of health disorders. The review could help to develop novel genistin medicine with significant health benefits for application in the nutraceutical and pharmaceutical fields.

Address: College of Veterinary Medicine, Jeonbuk National University, Iksan, 54596, South Korea.; Department of Livestock Production and Management, Sylhet Agricultural University, Sylhet, 3100, Bangladesh.; Department of Physiology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh.; Department of Pharmacology and Toxicology, Sylhet Agricultural University, Sylhet, 3100, Bangladesh. [email protected].

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