Uranium in drinking water: a public health threat.

Geir Bjørklund, Yuliya Semenova, Lyudmila Pivina, Maryam Dadar, Md Mostafizur Rahman, Jan Aaseth, Salvatore Chirumbolo

Journal: Archives of toxicology 2021;94(5):1551-1560

PMID: 32065295

Abstract

Uranium (U) has no known essential biological functions. Furthermore, it is well known for its toxicity, radioactivity, and carcinogenic potency. Impacts on human health due to U exposure have been studied extensively by many researchers. Chronic exposure to low-level U isotopes (radionuclides) may be interlinked with cancer etiology and at high exposure levels, also kidney disease. Other important issues covered U and fertilizers, and also U in soils or human tissues as an easily measurable indicator element in a pathophysiological examination. Furthermore, phosphate fertilization is known as the important source of contamination with U in the agricultural land, mainly due to contamination in the phosphate rock applied for fertilizer manufacture. Therefore, long-term usage of U-bearing fertilizers can substantially increase the concentration of U in fertilized soils. It should also be noted that U is an active redox catalyst for the reaction between DNA and HO. This review is aimed to highlight a series on various hydro-geochemical aspects in different water sources and focused on the comparison of different U contents in the drinking water sources and presentation of data in relation to health issues.

Address: Council for Nutritional and Environmental Medicine (CONEM), Toften 24, 8610, Mo i Rana, Norway. [email protected].; Semey Medical University, Semey, Kazakhstan.; CONEM Kazakhstan Environmental Health and Safety Research Group, Semey Medical University, Semey, Kazakhstan.; Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran.; Department of Environmental Sciences, Jahangirnagar University, Dhaka, Bangladesh.; CONEM Bangladesh Trace and Radioactive Elements Research Group, Department of Environmental Sciences, Jahangirnagar University, Dhaka, Bangladesh.; Research Department, Innlandet Hospital Trust, Brumunddal, Norway.; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.; CONEM Scientific Secretary, Verona, Italy.

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