A program of exercise, brain training, and lecture to prevent cognitive decline.

Minoru Kouzuki, Toshiaki Kato, Kenji Wada-Isoe, Shinya Takeda, Atsuhito Tamura, Yuichi Takanashi, Shintaro Azumi, Yoshinori Kojima, Chikako Maruyama, Maki Hayashi, Michimi Itou, Katsuya Urakami

Journal: Annals of clinical and translational neurology 2021;7(3):318-328

PMID: 32068975

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Abstract

OBJECTIVE

We examined the benefits of a community-based program combining physical exercise, cognitive training, and education on dementia and lifestyle habits.

METHODS

This crossover open-label trial included 141 community-dwelling elderly people with suspected mild cognitive decline (MCD). Subjects were assigned to a 6-month intervention-first/6-month observation-second (INT-OBS) group or an OBS-INT group. The 6-month intervention consisted of 2 h of physical exercise, cognitive training, and classroom study or rest once weekly. Primary outcome was change in Touch Panel-type Dementia Assessment Scale (TDAS) score.

RESULTS

TDAS score improved significantly during the intervention period compared with the observation period for all subjects (P < 0.05). Some physical functions also improved significantly during the intervention period compared with the observation period in the OBS-INT group (P < 0.05).

INTERPRETATION

This community-based program improved both cognitive and physical function in elderly people with suspected MCD.

Address: Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University, 86, Nishi-cho, Yonago, 683-8503, Japan.; Division of Medical Science in Sports and Exercise, Department of Social Medicine, Faculty of Medicine, Tottori University, 4-101 Koyama-cho Minami, Tottori, 680-8550, Japan.; Division of Neurology, Department of Brain and Neurological Sciences, Faculty of Medicine, Tottori University, 36-1, Nichi-cho, Yonago, 683-8504, Japan.; Department of Dementia Research, Kawasaki Medical School, 2-6-1, Nakasange, Kita-Ku, Okayama, 700-8505, Japan.; Department of Clinical Psychology, Tottori University Graduate School of Medical Sciences, 86, Nishi-cho, Yonago, 683-8503, Japan.; The Nanbu Town National Health Insurance Saihaku Hospital, 397, Yamato, Nanbu-cho, Saihaku, 683-0323, Japan.; Department of Occupational Therapist, YMCA College of Medical & Human Services in Yonago, 3-3-2, Kinkai-cho, Yonago, Tottori, 683-0825, Japan.; Tottori Association of Occupational Therapists, 3-3-2, Kinkai-cho, Yonago, Tottori, 683-0825, Japan.; Department of Rehabilitation, Satoni Den-en Clinic, 54-2, Satoni, Tottori-shi, Tottori, 680-0935, Japan.; Tottori Physical Therapy Association, 212-5, Dakyojicho, Kurayoshi, 682-0816, Japan.; Social Welfare Corporation Kohen, Nursing home Sakaikohen, 2083, Seido-cho, Sakaiminato, 684-0063, Japan.; Kotoura Town Hall, 591-2, Tokuman, Kotoura-cho, Touhakugunn, 689-2392, Japan.; Yonago Public Comprehensive Support Center for Shoutoku-Community, 1238 Ishii, Yonago, Tottori, 683-0021, Japan.

DOI: 10.1002/acn3.50993

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MeSH Terms: Aged, Aged, 80 and over, Cognitive Dysfunction, Cognitive Remediation, Combined Modality Therapy, Cross-Over Studies, Dementia, Exercise Therapy, Female, Humans, Independent Living, Life Style, Male, Neuropsychological Tests, Outcome Assessment, Health Care, Patient Education as Topic