The emerging role of skeletal muscle mitochondrial dynamics in exercise and ageing.

Rafael A Casuso, Jesús R Huertas

Journal: Ageing research reviews 2020;58():101025

PMID: 32018055

Full Text on Elsevier Science View on PubMed

Abstract

["Mitochondria are the hub for energy production within living cells. They can undergo morphological changes in response to nutrient availability and cellular stress. Here, we review how exercise chronically and acutely affects mitochondrial dynamics. Moreover, we discuss whether mitochondrial dysfunction observed in elderly subjects is due to the ageing process per se or due to the associated sedentary state. Finally, we study how endurance exercise can improve mitochondrial dynamics in older subjects, thereby improving their overall health and likely limiting muscle waste.",{"copyright":"Copyright \u00a9 2020 Elsevier B.V. All rights reserved."}]

Address: Institute of Nutrition and Food Technology, Biomedical Research Centre, Department of Physiology, Faculty of Sport Sciences, University of Granada, Avda del conocimiento s/n. 18016 Armilla, Granada, Spain. Electronic address: [email protected].; Institute of Nutrition and Food Technology, Biomedical Research Centre, Department of Physiology, Faculty of Sport Sciences, University of Granada, Avda del conocimiento s/n. 18016 Armilla, Granada, Spain.

DOI: 10.1016/j.arr.2020.101025

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MeSH Terms: Aged, Aging, Exercise, Humans, Mitochondria, Muscle, Mitochondrial Dynamics, Mitochondrial Proteins, Muscle, Skeletal