Female child with hematidrosis of the palm: Case report and published work review.

Hiroyuki Murota, Yorihisa Kotobuki, Kosuke Yamaga, Yoshichika Yoshioka

Journal: The Journal of dermatology 2020;47(2):166-168

PMID: 31793058

Abstract

Hematidrosis is a rare disorder involving spontaneous excretion of sweat contaminated by blood cells. We report the case of a 6-year-old girl with hematidrosis from her palms with no underlying disease or psychotic disorder. Before the onset of this symptom, the patient was given an indoor horizontal exercise bar with which she had been frequently playing. This symptom appeared without apparent triggers and was not associated with subjective symptoms. To examine her hematidrosis, metabolites in the red bodily fluid were analyzed using nuclear magnetic resonance analysis. We found the fluid had a metabolome profile similar to that of eccrine sweat. Pathological analysis revealed no abnormal findings, including expression of the tight junction protein claudin 3. Her symptom decreased after treatment with tap-water iontophoresis. Here, we describe our case and discuss its etiology by reviewing previous reports.

© 2019 Japanese Dermatological Association.

Address: Department of Dermatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.; Department of Dermatology, Course of Integrated Medicine, Graduate School of Medicine, Osaka University, Suita, Japan.; Biofunctional Imaging Lab, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.
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