Myths and realities of range uncertainty.

Antony John Lomax

Journal: The British journal of radiology 2020;93(1107):20190582

PMID: 31778317

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Abstract

Range uncertainty is a much discussed topic in proton therapy. Although a very real aspect of proton therapy, its magnitude and consequences are sometimes misunderstood or overestimated. In this article, the sources and consequences of range uncertainty are reviewed, a number of myths associated with the effect discussed with the aim of putting range uncertainty into clinical context and attempting to de-bunk some of the more exaggerated claims made as to its consequences.

Address: Centre for Proton Therapy, Paul Scherrer Institute, Switzerland and Department of Physics, ETH Zurich, Switzerland.

DOI: 10.1259/bjr.20190582

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MeSH Terms: Absorption, Radiation, Humans, Neoplasms, Radiation-Induced, Patient Positioning, Photons, Proton Therapy, Radiotherapy Dosage, Treatment Outcome, Uncertainty, Water