The allergenic relevance of profilin (Ole e 2) from Olea europaea pollen.

A Martínez, J A Asturias, J Monteseirín, V Moreno, A García-Cubillana, M Hernández, A de la Calle, C Sánchez-Hernández, J L Pérez-Formoso, J Conde

Journal: Allergy 2002;57 Suppl 71():17-23

PMID: 12173264

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Abstract

Many works have dealt with the study of the allergenic relevance of profilin from allergenic extracts, mainly derived from pollens and vegetable foods. Olive pollen extracts also contain a profilin allergen (Ole e 2). This protein has been characterized in detail, so the amino-acid sequence of three isoforms and the structural model of one of them are already known. The prevalence of Ole e 2 for olive allergenic patients has been evaluated by different in vivo and in vitro methods, and the results compared with those obtained for another pollen profilins.

Address: Hospital Virgen Macarena, Servicio de Alergia, Ville, Spain.

DOI: 10.1034/j.1398-9995.2002.057s71017.x

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MeSH Terms: Allergens, Amino Acid Sequence, Contractile Proteins, Humans, Microfilament Proteins, Models, Molecular, Molecular Sequence Data, Olea, Pollen, Profilins