Stephen T Magill, Theodore H Schwartz, Philip V Theodosopoulos, Michael W McDermott
Abstract
["Interstitial intracranial radiotherapy implants, or brachytherapy, is an adjuvant option for treatment of recurrent high-grade meningiomas after resection. The implants are placed in the resection cavity following tumor resection. The most commonly used isotope is Iodine-125 (I-125). While there are no controlled studies comparing treatment of meningiomas with or without brachytherapy, several case series report good long-term survival, suggesting that this may be a useful adjuvant for recurrent high-grade tumors. Complications can occur including radiation necrosis, impaired wound healing, hydrocephalus and infection. In the future, new isotopes are being explored that may have fewer complications and better safety profiles.",{"copyright":"Copyright \u00a9 2020 Elsevier B.V. All rights reserved."}]
Address:
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, United States.; Department of Neurosurgery, Otolaryngology and Neuroscience, Weill Cornell Medicine, New York, NY, United States.; Miami Neuroscience Institute, Baptist Health of South Florida, Miami, FL, United States; Division of Neuroscience, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States. Electronic address:
[email protected].