The Phytochemistry and Pharmacology of Hypericum.

Chuan-Yun Xiao, Qing Mu, Simon Gibbons

Journal: Progress in the chemistry of organic natural products 2021;112():85-182

PMID: 33306173

Abstract

["Hypericum L. is a genus of the family Hypericaceae within the dicotyledones. The constituents of Hypericum species are valued for their important biological properties. Their use is in the treatment of depression and as antibacterial agents has been well documented in the primary literature and in ethnobotanical reports. The present contribution gives a comprehensive summary of the chemical constituents of members of the genus Hypericum and their biological effects. A detailed account of the chemical constituents, including phloroglucinol derivatives, xanthones, dianthrones, and flavonoids, is included. These compounds show a diverse range of biological activities that include antimicrobial, cytotoxic, antidepressant-like, and antinociceptive effects."]

Address: Department of Natural Medicine, School of Pharmacy, Shanghai Engineering Research Center of Immuno Therapeutics, Fudan University, 826 Zhangheng Road, Zhangjiang Pudong, Shanghai, 201203, China. [email protected].; Department of Natural Medicine, School of Pharmacy, Shanghai Engineering Research Center of Immuno Therapeutics, Fudan University, 826 Zhangheng Road, Zhangjiang Pudong, Shanghai, 201203, China.; School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.

DOI: 10.1007/978-3-030-52966-6_2

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https://dx.doi.org/10.1007/978-3-030-52966-6_2

MeSH Terms: Anti-Infective Agents, Antidepressive Agents, Hypericum, Plant Extracts