Osteointegration of a Biocomposite Suture Anchor After Arthroscopic Shoulder Labral Repair.

Hiroyuki Sugaya, Kazuhide Suzuki, Hideya Yoshimura, Minoru Tanaka, Tetsuya Yamazaki, Mikihiko Watanabe, Hiroshi Iwaso, Tsutomu Inaoka, Hideharu Sugimoto, Keisuke Matsuki, Motohiko Mikasa

Journal: Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2020;35(12):3173-3178

PMID: 31734043

Full Text on Elsevier Science View on PubMed

Abstract

PURPOSE

To evaluate osteoconductivity of a poly-L-lactide co-glycolide (PLG)-calcium sulfate (CS)-β-tricalcium phosphate (β-TCP) biocomposite suture anchor after arthroscopic shoulder labral repair.

METHODS

The subjects of this study were patients who participated in a clinical trial for acquisition of marketing approval of a PLG-CS-β-TCP biocomposite anchor in Japan. They underwent arthroscopic labral repair using the anchor, and computed tomographic (CT) images of the glenoid were obtained 2 years after surgery. Osteoconductivity at the anchor sites was evaluated with the CT images using the established ossification quality score. Shoulder function scores including the Rowe score and Japanese Shoulder Society shoulder instability score were also assessed 2 years after surgery.

RESULTS

CT images and functional scores were obtained from 37 patients, comprising 29 men and 8 women with a mean age of 29 years (range, 25-33 years) at surgery. A total of 148 anchors were implanted in the 37 shoulders. Osteoconductivity was seen in 133 of 148 anchor sites (90.0%) 2 years after implantation. No significant differences in osteoconductivity were found by anchor diameter or position. The Rowe score significantly improved from 39.9 points (95% confidence interval [CI], 33.8-45.9 points) preoperatively to 96.6 points (95% CI, 95.1-98.1 points) at 2 years postoperatively (P < .001). The Japanese Shoulder Society shoulder instability score also significantly improved, from 63.1 points (95% CI, 58.4-67.7 points) preoperatively to 96.3 points (95% CI, 94.7-97.8 points) at 2 years postoperatively (P < .001).

CONCLUSIONS

Biocomposite suture anchors made of PLG, CS, and β-TCP exhibited some osteoconductivity 2 years after arthroscopic labral repair, as well as good clinical outcomes.

LEVEL OF EVIDENCE

Level IV, therapeutic case series.

Address: Sports Medicine & Joint Center, Funabashi Orthopaedic Hospital, Funabashi, Japan. Electronic address: [email protected].; Department of Sports Medicine, Asao General Hospital, Kawasaki, Japan.; Department of Orthopaedic Surgery, Kawaguchi Kogyo General Hospital, Kawaguchi, Japan.; Department of Orthopaedic Surgery, Tohoku Rosai Hospital, Sendai, Japan.; Department of Sports Medicine, Yokohama Minami Kyosai Hospital, Kawasaki, Japan.; Department of Orthopaedic Surgery, Tokyo Asuka Hospital, Setagaya, Japan.; Department of Sports Medicine, Kantoh Rosai Hospital, Kawasaki, Japan.; Department of Radiology, Toho University Sakura Medical Center, Sakura, Japan.; Department of Radiology, Jichi Medical University School of Medicine, Shimotsuke, Japan.; Sports Medicine & Joint Center, Funabashi Orthopaedic Hospital, Funabashi, Japan.; Matsudo Orthopaedic Hospital, Matsudo, Japan.

DOI: 10.1016/j.arthro.2019.06.023

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https://medlineplus.gov/dislocatedshoulder.html

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https://antibodies.cancer.gov/detail/CPTC-BRIP1-5

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MeSH Terms: Adult, Arthroplasty, Biocompatible Materials, Calcium Phosphates, Female, Humans, Japan, Joint Instability, Male, Osteogenesis, Polyesters, Postoperative Period, Shoulder Dislocation, Shoulder Joint, Suture Anchors, Tomography, X-Ray Computed