Active-electrode biosensor of SnO nanowire for cyclodextrin detection from microbial enzyme.

Cleber A Amorim, Kate C Blanco, Ivani M Costa, Eduardo F Vicente, João Flávio da S Petruci, Jonas Contiero, Edson R Leite, Adenilson J Chiquito

Journal: Nanotechnology 2020;31(16):165501

PMID: 31770731

Abstract

Cyclodextrin (CD) is a conical compound used in food and pharmaceutical industry to complexation of hydrophobic substances. It is a product of microbial enzymes which converts starch into CD during their activity. We aim to detect CD using active-electrode biosensor of SnO. They were grown on active electrode by the VLS method. The CD consists of several glucose units which have hydroxyl groups which tend to bind to interface states present in nanowires changing their conductivity. Experimental results of electrical conductivity at different CD concentrations are presented. A model that describes the influence of adsorbed glucose on nanowires and its electrical properties is also presented. Some general observations are performed on the applicability of the CD adsorption method by the nanowire-based biosensor.

Address: Universidade Estadual Paulista, Faculdade de Ciências e Engenharia de Tupã, Tupã, Av. Domingos da Costa Lopes, 780 Jardim Itaipu, Tupã, SP, Brazil.

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