Clinical utility of arterial spin labeling imaging in disorders of the nervous system.

Sauson Soldozy, Jacob Galindo, Harrison Snyder, Yusuf Ali, Pedro Norat, Kaan Yağmurlu, Jennifer D Sokolowski, Khadijeh Sharifi, Petr Tvrdik, Min S Park, M Yashar S Kalani

Journal: Neurosurgical focus 2020;47(6):E5

PMID: 31786550

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Abstract

Neuroimaging is an indispensable tool in the workup and management of patients with neurological disorders. Arterial spin labeling (ASL) is an imaging modality that permits the examination of blood flow and perfusion without the need for contrast injection. Noninvasive in nature, ASL provides a feasible alternative to existing vascular imaging techniques, including angiography and perfusion imaging. While promising, ASL has yet to be fully incorporated into the diagnosis and management of neurological disorders. This article presents a review of the most recent literature on ASL, with a special focus on its use in moyamoya disease, brain neoplasms, seizures, and migraines and a commentary on recent advances in ASL that make the imaging technique more attractive as a clinically useful tool.

DOI: 10.3171/2019.9.FOCUS19567

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https://thejns.org/doi/10.3171/2019.9.FOCUS19567

MeSH Terms: Brain Diseases, Brain Neoplasms, Cerebral Angiography, Cerebral Arteries, Cerebrovascular Circulation, Glioma, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Meningeal Neoplasms, Meningioma, Migraine Disorders, Moyamoya Disease, Neuroimaging, Protons, Radio Waves, Seizures, Water