FinnTwin16: A Longitudinal Study from Age 16 of a Population-Based Finnish Twin Cohort.

Milla Kaidesoja, Sari Aaltonen, Leonie H Bogl, Kauko Heikkilä, Sara Kaartinen, Urho M Kujala, Ulla Kärkkäinen, Guiomar Masip, Linda Mustelin, Teemu Palviainen, Kirsi H Pietiläinen, Mirva Rottensteiner, Pyry N Sipilä, Richard J Rose, Anna Keski-Rahkonen, Jaakko Kaprio

Journal: Twin research and human genetics : the official journal of the International Society for Twin Studies 2020;22(6):530-539

PMID: 31796134

Full Text on Cambridge University Press View on PubMed

Abstract

The purpose of this review is to provide a detailed and updated description of the FinnTwin16 (FT16) study and its future directions. The Finnish Twin Cohort comprises three different cohorts: the Older Twin Cohort established in the 1970s and the FinnTwin12 and FT16 initiated in the 1990s. FT16 was initiated in 1991 to identify the genetic and environmental precursors of alcoholism, but later the scope of the project expanded to studying the determinants of various health-related behaviors and diseases in different stages of life. The main areas addressed are alcohol use and its consequences, smoking, physical activity, overall physical health, eating behaviors and eating disorders, weight development, obesity, life satisfaction and personality. To date, five waves of data collection have been completed and the sixth is now planned. Data from the FT16 cohort have contributed to several hundred studies and many substudies, with more detailed phenotyping and collection of omics data completed or underway. FT16 has also contributed to many national and international collaborations.

Address: Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.; Department of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland.; Nightingale Health Ltd., Helsinki, Finland.; Obesity Research Unit, Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Obesity Center, Endocrinology, Abdominal Center, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland.; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.; Department of Medicine, Central Finland Health Care District, Jyväskylä, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.; Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN, USA.

DOI: 10.1017/thg.2019.106

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MeSH Terms: Alcohol Drinking, Alcoholism, Diseases in Twins, Finland, Humans, Incidence, Longitudinal Studies, Mental Disorders, Registries, Smoking, Twin Studies as Topic, Twins