Isoniazid-induced encephalopathy in an end-stage renal disease patient - A case report and literature review.

J M Low, K W Wong

Journal: The Medical journal of Malaysia 2020;74(6):553-554

PMID: 31929489

Free Full Text on Malaysian Medical Association View on PubMed

Abstract

Patients with end stage renal disease have higher risk of tuberculosis due to lower cell-mediated immunity. Standard regime of anti-tuberculosis contains isoniazid where neurological side effects such as seizure and encephalopathy have been documented. We present a case of isoniazid-induced encephalopathy in a haemodialysis patient. A literature review on isoniazid-induced encephalopathy was done. Recognition of this condition is important as it is reversible with cessation of isoniazid and institution of high dose pyridoxine.

Address: Hospital Keningau, Keningau, Department of Internal Medicine, Sabah, Malaysia. [email protected].; Hospital Queen Elizabeth, Department of Nephrology, Kota Kinabalu, Sabah, Malaysia.

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Full Text Sources:

http://www.e-mjm.org/2019/v74n6/end-stage-renal-di...

Medical:

https://medlineplus.gov/braindiseases.html

MeSH Terms: Antitubercular Agents, Brain Diseases, Female, Humans, Isoniazid, Kidney Failure, Chronic, Middle Aged, Renal Dialysis, Tuberculosis, Pulmonary