Cytosolic glucocorticoid receptor-interacting proteins.

A C Wikström, C Widén, A Erlandsson, E Hedman, J Zilliacus

Journal: Ernst Schering Research Foundation workshop 2003

PMID: 12355716

Abstract

Studies of GR-interacting proteins can provide valuable insights into the regulation of GR cellular signalling. The cytoplasmic localization of GR and reports of GR interaction with such a plethora of other cytoplasmic proteins may point to a unique role for GR in modulating and integrating other signalling pathways. A better insight into these interactions could serve as a tool when trying to understand and modify GR signalling.

Address: Department of Medical Nutrition Karolinska Institute, Huddinge University Hospital, Novum F60, S-141 86 Huddinge, Sweden. [email protected]

DOI: 10.1007/978-3-662-04660-9_11

MeSH Terms: 14-3-3 Proteins, Cytoskeletal Proteins, Cytosol, Humans, Molecular Chaperones, NF-kappa B, Protein Binding, Proto-Oncogene Proteins c-raf, Receptors, Glucocorticoid, Tyrosine 3-Monooxygenase