Corneal refractive surgery combined with simultaneous corneal cross-linking: Indications, protocols and clinical outcomes-A review.

Jiaonan Ma, Yan Wang, Vishal Jhanji

Journal: Clinical & experimental ophthalmology 2021;48(1):78-88

PMID: 31487097

Abstract

Corneal refractive surgery is one of the most common approaches for correction of refractive errors. Combined corneal refractive surgery and corneal cross-linking (CXL) has been proposed as a method to achieve better refractive stability and to prevent iatrogenic corneal ectasia. However, there are concerns regarding its indications, surgical safety, standardization of protocols and long-term effect on corneal tissue. This review article aims to discuss the current knowledge and recent updates on combination of CXL and refractive surgery.

Address: Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.; College of Ophthalmology, Tianjin Medical University, Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Lab of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital, Tianjin, China.; UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

DOI: 10.1111/ceo.13621

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https://doi.org/10.1111/ceo.13621

MeSH Terms: Collagen, Combined Modality Therapy, Corneal Pachymetry, Corneal Stroma, Corneal Surgery, Laser, Cross-Linking Reagents, Humans, Photochemotherapy, Photosensitizing Agents, Refraction, Ocular, Refractive Errors, Riboflavin, Ultraviolet Rays, Visual Acuity