Utilization of Cu-nanoparticles as medication agent to reduce atherosclerotic lesions of a bifurcated artery having compliant walls.

Iqra Shahzadi, Sana Suleman, S Saleem, S Nadeem

Journal: Computer methods and programs in biomedicine 2021;184():105123

PMID: 31627154

Abstract

OBJECTIVE

A theoretical analysis is presented to study the bio-nanofluid with copper as medication agent for atherosclerotic bifurcated artery with flexible walls.

DESIGN/APPROACH

The circulatory framework in human body is comprised of a system of veins that incorporate the bifurcation in this way the impact of copper nanoparticles on parent, at apex and on daughter artery regions (in the wake of being bifurcated) is watched. Streaming of blood along vessel segment is recognized to be newtonian. The consistent idea of the atherosclerotic arterial wall is additionally considered to make relationship with permeability aspects with arterial wall thickness. Copper nanoparticles are utilized to reduce the atherosclertic lesions for bifurcated stenotic artery.

FINDINGS

The designed equations along with the experimental values of copper nanoparticles and blood are utilized for theoretical investigation. Moreover, hemodynamics impacts are also figure out to examine the flow of blood for atherosclertic artery. Comparison between parent and daughter artery is plotted through velocity profile. To see the theoretical assistance of this copper mediated model in biomedical field, graphical illustration is presented. At the end, noticed that the inclusion of copper nanoparticles enhances the velocity significantly both for parent as well as daughter artery.

CONCLUSIONS

The circulation of blood is considered to be different from pressure between portions of atherosclerotic and non-atherosclerotic artery. Shear stress is reduces by changing the bifurcation angle for daughter artery while trend is reversed for parent artery. The size of inner circularting bolus decreases by changing compliant parameter for parent artery while shape is changed for daughter artery.

Copyright © 2019. Published by Elsevier B.V.

Address: Department of Mathematics, Air University, PAF Complex E-9, Islamabad 44000, Pakistan. Electronic address: [email protected].; Department of Mathematics, Quaid-i-Azam University, 45320, Islamabad 44000, Pakistan.; Department of Mathematics, College of Sciences, King Khalid University, Abha 61413, Saudi Arabia.
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