Intravenous iron: the iatrogenic kick to lose control over oxygen?

W H Hörl, R Deicher

Journal: Kidney & blood pressure research 2003;25(5):284-8

PMID: 12435873

Full Text on S. Karger AG, Basel, Switzerland View on PubMed

Abstract

Effective erythropoiesis requires both erythropoietin and iron. Regular, intravenous iron supplements represent a standard adjuvant therapy for the treatment of anemia of chronic kidney disease. In this paper, the authors speculate upon potential deleterious effects of intravenous iron on cellular physiology in the setting of the increased oxidant burden of hemodialysis patients.

Address: Universitätsklinik für Innere Medizin III, Klinische Abteilung für Nephrologie und Dialyse, Wien, Osterreich. [email protected]

DOI: 10.1159/000066793

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MeSH Terms: Anemia, Humans, Iatrogenic Disease, Injections, Intravenous, Iron, Kidney Failure, Chronic, Oxidative Stress, Renal Dialysis