One Anastomosis Gastric Bypass-Mini Gastric Bypass with Tailored Biliopancreatic Limb Length Formula Relative to Small Bowel Length: Preliminary Results.

Iman Komaei, Federica Sarra, Claudio Lazzara, Michele Ammendola, Riccardo Memeo, Giuseppe Sammarco, Giuseppe Navarra, Giuseppe Currò

Journal: Obesity surgery 2020;29(9):3062-3070

PMID: 31209832

Abstract

BACKGROUND

One Anastomosis Gastric Bypass-Mini Gastric Bypass (OAGB-MGB) is rapidly gaining popularity and is currently being performed by an increasing number of bariatric surgeons worldwide. However, excessive postoperative weight loss and malnutrition still remain a major concern regarding this procedure. The aim of this observational retrospective study was to investigate whether a tailored biliopancreatic limb (BPL) length relative to small bowel length (SBL) is superior to a fixed BPL length of 200 cm in terms of weight loss results and nutritional deficiencies in morbidly obese patients 1 year following OAGB-MGB.

MATERIALS AND METHODS

Sixty-four patients who underwent OAGB-MGB were divided into two consecutive groups depending on the BPL length used: fixed 200-cm BPL and tailored BPL groups. Anthropometric measurements (%EWL, TWL, %TWL) and nutritional parameters (vitamin A, vitamin D, vitamin B, serum iron, serum albumin, total protein) were compared between the two groups at 1-year follow-up.

RESULTS

No statistically significant differences were observed between the patients in two groups in terms of %EWL, TWL, %TWL. The number of patients with deficiencies of vitamin A (p = 0.030), vitamin D (p = 0.020), and albumin (p = 0.030) was significantly higher in fixed 200-cm BPL group as compared with tailored BPL group, 1 year following OAGB-MGB. No statistically significant differences were seen between the patients in two groups in terms of vitamin B iron, and total protein deficiencies.

CONCLUSION

Tailoring BPL length by bypassing about 40% of the SBL seems to be safe and effective. According to preliminary results of this study, a tailored BPL length relative to SBL is even likely to be superior to the fixed 200-cm BPL as it is associated with less nutritional deficiencies while providing similar weight loss results. Further randomized studies with larger sample sizes and longer follow-up periods are necessary to confirm the primary results of this study.

Address: Department of Human Pathology of Adult and Evolutive Age, University of Messina, Messina, Italy.; Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.; Department of Emergency and Organ Transplantation, University Aldo Moro of Bari, Bari, Italy.; Department of Human Pathology of Adult and Evolutive Age, University of Messina, Messina, Italy. [email protected].; Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy. [email protected].

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