It takes a village: primary care of the pediatric liver transplant recipient.

Sara Hassan, Vicky Lee Ng, Amal Aqul

Journal: Current opinion in pediatrics 2020;31(5):636-644

PMID: 31369476

Abstract

PURPOSE OF REVIEW

Long-term survival is now the rule rather than the exception for infants and children who undergo liver transplantation for end-stage liver disease, metabolic liver conditions and a variety of other indications. Pediatricians and primary care providers play vital roles in the care and management of this patient population. The purpose of this review is to highlight key aspects important to the care of the pediatric liver transplant recipient.

RECENT FINDINGS

Significant advances in immunosuppressive therapies and surgical techniques have contributed to improved graft and patient survival rates, shifting the focus beyond immediate survival to strategies to minimize comorbidities related to long-term immunosuppression during growing years, attend to patient and parent-reported outcomes and enhance quality of life. A multidisciplinary approach allows for monitoring and surveillance of both routine (growth, nutritional rehabilitation, cognitive development, mental and psychosocial health, contraception and daily activities) and transplant-related (adverse effects of immunosuppression, susceptible infections, extra-hepatic systems, transition from childhood to adolescence to adulthood) themes.

SUMMARY

Effective communication between the primary care physician and the transplant team is imperative for optimizing best outcomes. The primary care provider should be aware of the multifacet nature of posttransplant management, which includes medication regimens, common complications and infections.

Address: Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Texas Southwestern, Dallas, Texas, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Toronto.; SickKids Transplant and Regenerative Medicine Center, Hospital for Sick Children, Toronto, Ontario, Canada.
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