Ethnopharmacology, Phytochemistry, Pharmacology, Toxicology and Clinical Applications of Radix Astragali.

Chun-Hong Zhang, Xiao Yang, Jing-Ran Wei, Na-Mu-Han Chen, Jian-Ping Xu, Ya-Qiong Bi, Min Yang, Xue Gong, Zi-Yan Li, Kai Ren, Qi-Heng Han, Lei Zhang, Xue Li, Ming-Yue Ji, Cong-Cong Wang, Min-Hui Li

Journal: Chinese journal of integrative medicine 2021;27(3):229-240

PMID: 31502185

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Abstract

Radix Astragali (RA), a traditional Chinese medicine from the dried root of Astragalus species, is widely distributed throughout the temperate regions of the world. The major bioactive constituents of RA are triterpene glycosides, flavonoids, saponins, and alkaloids, and these compounds mostly exert pharmacological activities on the cardiovascular, immune, respiratory, and hepatic systems. This review summarizes the recent studies on RA and provides a comprehensive summary regarding the status of resources, ethnopharmacology, phytochemistry, pharmacology, toxicology, clinical application, and patent release of RA. We hope this review can provide a guidance for further development of therapeutic agents from RA.

Address: Department of Pharmacy, Baotou Medical College, Baotou, Inner Mongolia Autonomous Region, 014040, China.; Department of Pharmacy, Inner Mongolia Medical University, Hohhot, 010020, China.; Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China.; Department of Pharmacy, Baotou Medical College, Baotou, Inner Mongolia Autonomous Region, 014040, China. [email protected].; Pharmaceutical Laboratory, Inner Mongolia Institute of Traditional Chinese Medicine, Hohhot, 010020, China. [email protected].

DOI: 10.1007/s11655-019-3032-8

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https://dx.doi.org/10.1007/s11655-019-3032-8

MeSH Terms: Astragalus propinquus, Drugs, Chinese Herbal, Ethnopharmacology, Medicine, Chinese Traditional, Phytochemicals, Phytotherapy