The effects of a sleep/recovery supplement: 'Night Time Recharge' on sleep parameters in young adults.

Trevor Simper, Molly Gilmartin, Daniel Allwood, Luke Taylor, Andrew Chappell

Journal: Nutrition and health 2020;25(4):265-274

PMID: 31512550

Abstract

BACKGROUND

Concentrated cherry juice reportedly contains melatonin which, in turn, has been highlighted as an important regulator in initiating sleep.

AIM

The present investigation aims to clarify whether Night Time Recharge (NTR), a marketed sleep aid containing cherry extract, improves key sleep parameters in young, active adults with mildly poor sleep.

METHODS

A double-blind, randomized, placebo-controlled, cross-over study design was employed. Twenty participants (nine female) consumed either NTR or a placebo for seven days. Accelerometers were used to assess sleep quality and physical activity levels. Urinary levels of 6-sulphatoxymelatonin (6-SMT), a marker of melatonin synthesis, was assessed via enzyme-linked immunosorbent assay.

RESULTS

6-SMT levels increased following NTR treatment (28.95 ng/ml) compared with placebo (4.0 ng/ml) ( < 0.001). There was also a significant difference ( = 0.047) in dietary tryptophan consumption during the NTR treatment (1236 mg) versus placebo (1149 mg). No trace of melatonin was detected from our analysis of the supplement. NTR had no significant effect on any sleep parameters with the exception of sleep latency ( = 0.001).

CONCLUSIONS

As chemical analysis of NTR by liquid-chromatography mass-spectrometry identified no detectable melatonin, the tryptophan content of the supplement is a likely reason for improvement in sleep latency. These results are in contrast to previous studies which have found a positive effect on sleep following cherry supplementation. Future work should focus on sleep latency and investigating whether cherry juice is effective in participants with problems in initiating sleep.

Address: Food and Nutrition group, Sheffield Hallam University, Sheffield, UK.; Department of Biosciences and Chemistry, Sheffield Hallam University, Sheffield, UK.; School of Pharmacy and Life Science, Robert Gordon University, Aberdeen, UK.
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