An Update: Portal Hypertensive Gastropathy and Colopathy.

Don C Rockey

Journal: Clinics in liver disease 2020;23(4):643-658

PMID: 31563216

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Abstract

Complications of portal hypertension include portal hypertensive gastropathy and colopathy. These disorders may cause chronic or acute gastrointestinal bleeding. The diagnosis is made endoscopically; therefore, there is great variability in their assessment. Portal hypertensive gastropathy can range from a mosaic-like pattern resembling snakeskin mucosa to frankly bleeding petechial lesions. Portal hypertensive colopathy has been less well-described and is variably characterized (erythema, vascular lesions, petechiae). Treatment is challenging and results are inconsistent. Currently, available evidence does not support the use of beta-blockers for primary prevention. Further investigation of the pathogenesis, natural history, and treatment of these disorders is needed.

Address: Department of Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 803, Charleston, SC 29425, USA. Electronic address: [email protected].

DOI: 10.1016/j.cld.2019.07.002

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MeSH Terms: Adrenergic beta-Antagonists, Anemia, Iron-Deficiency, Argon Plasma Coagulation, Colonic Diseases, Colonoscopy, Endoscopy, Digestive System, Gastrointestinal Hemorrhage, Humans, Hypertension, Portal, Ligation, Liver Cirrhosis, Portasystemic Shunt, Transjugular Intrahepatic, Sclerotherapy, Stomach Diseases