Biotechnological Production of Organic Acids from Renewable Resources.

Daniel Pleissner, Donna Dietz, Jozef Bernhard Johann Henri van Duuren, Christoph Wittmann, Xiaofeng Yang, Carol Sze Ki Lin, Joachim Venus

Journal: Advances in biochemical engineering/biotechnology 2019;166():373-410

PMID: 28265703

Abstract

Biotechnological processes are promising alternatives to petrochemical routes for overcoming the challenges of resource depletion in the future in a sustainable way. The strategies of white biotechnology allow the utilization of inexpensive and renewable resources for the production of a broad range of bio-based compounds. Renewable resources, such as agricultural residues or residues from food production, are produced in large amounts have been shown to be promising carbon and/or nitrogen sources. This chapter focuses on the biotechnological production of lactic acid, acrylic acid, succinic acid, muconic acid, and lactobionic acid from renewable residues, these products being used as monomers for bio-based material and/or as food supplements. These five acids have high economic values and the potential to overcome the "valley of death" between laboratory/pilot scale and commercial/industrial scale. This chapter also provides an overview of the production strategies, including microbial strain development, used to convert renewable resources into value-added products.

Address: Department of Bioengineering, Leibniz Institute for Agricultural Engineering and Bioeconomy Potsdam (ATB), Max-Eyth-Allee 100, 14469, Potsdam, Germany.; Institute of Systems Biotechnology, Saarland University, Saarbrücken, Germany.; School of Energy and Environment, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong.; Department of Bioengineering, Leibniz Institute for Agricultural Engineering and Bioeconomy Potsdam (ATB), Max-Eyth-Allee 100, 14469, Potsdam, Germany. [email protected].

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