Polyphenols: A concise overview on the chemistry, occurrence, and human health.

Alessandra Durazzo, Massimo Lucarini, Eliana B Souto, Carla Cicala, Elisabetta Caiazzo, Angelo A Izzo, Ettore Novellino, Antonello Santini

Journal: Phytotherapy research : PTR 2019;33(9):2221-2243

PMID: 31359516

Abstract

This review gives an updated picture of each class of phenolic compounds and their properties. The most common classification implies the subdivision of phenolics in two main groups: flavonoids (e.g., anthocyanins, flavanols, flavanones, flavonols, flavonones, and isoflavones) and non-flavonoids (e.g., phenolic acids, xanthones, stilbens, lignans, and tannins) polyphenols. The great interest in polyphenols is associated with their high potential application for food preservation and for therapeutic beneficial use. The relationship between polyphenol intake and human health has been exploited with special reference to cardiovascular diseases, hypertension, diabetes, metabolic syndrome, obesity, and cancer. The use of current existing databases of bioactive compounds including polyphenols is described as key tools for human health research.

© 2019 John Wiley & Sons, Ltd.

Address: CREA - Research Centre for Food and Nutrition, Rome, Italy.; Faculty of Pharmacy of University of Coimbra Azinhaga de Santa Comba, Coimbra, Portugal.; CEB-Centre of Biological Engineering, University of Minho, Braga, Portugal.; Department of Pharmacy, University of Napoli Federico II, Napoli, Italy.

Link outs

Bant logo

© Copyright 2026, Nutrition Evidence

NED wishes to thank the following organisations for their support:

We use cookies to improve your experience and analyze site traffic with Google Analytics. By continuing to use our site, you agree to our use of cookies. Learn more.