Catalytic oligonucleotides targeting EGR-1 as potential inhibitors of in-stent restenosis.

L M Khachigian

Journal: Annals of the New York Academy of Sciences 2002;947():412-5

PMID: 11795303

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Abstract

This brief review discusses recent strategies targeting the zinc finger transcription factor and immediate-early gene product Egr-1 with catalytic DNA in efforts to inhibit postangioplasty restenosis.

Address: Centre for Thrombosis and Vascular Research, The University of New South Wales, Sydney, Australia. [email protected]

DOI: 10.1111/j.1749-6632.2001.tb03975.x

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MeSH Terms: Angioplasty, Balloon, Coronary, Coronary Restenosis, DNA-Binding Proteins, Early Growth Response Protein 1, Humans, Immediate-Early Proteins, Stents, Transcription Factors