Management of atrial fibrillation in the emergency room and in the cardiology ward: the BLITZ AF study.

Michele Massimo Gulizia, Roberto Cemin, Furio Colivicchi, Leonardo De Luca, Andrea Di Lenarda, Giuseppe Boriani, Giuseppe Di Pasquale, Federico Nardi, Marino Scherillo, Donata Lucci, Gianna Fabbri, Aldo Pietro Maggioni

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2020;21(2):230-238

PMID: 30060174

Abstract

AIMS

To assess the number of admissions to the emergency room (ER) of patients with atrial fibrillation (AF) or atrial flutter (af) and their subsequent management. To evaluate the clinical profile and the use of antithrombotics and antiarrhythmic therapy in patients with AF admitted to cardiology wards.

METHODS AND RESULTS

BLITZ-AF is a multicentre, observational study conducted in 154 centres on patients with AF/af. In each centre, data were collected, retrospectively for 4 weeks in ER and prospectively for 12 weeks in cardiology wards. In ER, there were 6275 admissions. Atrial fibrillation was the main diagnosis in 52.9% of the cases, af in 5.9%. Atrial fibrillation represented 1.0% of all ER admissions and 1.7% of all hospital admissions. A cardioversion has been performed in nearly 25% of the cases. Out of 4126 patients, 52.2% were admitted in cardiology ward; mean age was 74 ± 11 years, 41% were females. Patients with non-valvular AF were 3848 (93.3%); CHA2DS2-VASc score was ≥2 in 87.4%. Cardioversion was attempted in 38.8% of the patients. In-hospital mortality was 1.2%. At discharge, 42.6% of the patients were treated with vitamin K antagonists, 39.5% with direct oral anticoagulants, 13.6% with other antithrombotic drugs, and 4.2% did not take any antithrombotic agent. Rate control strategy was pursued in 47.2%, rhythm control in 44.0%, 45.6% were discharged in sinus rhythm.

CONCLUSION

Atrial fibrillation still represents a significant burden on health care system. Oral anticoagulant use increased over time even if compliance with guidelines, with respect to prevention of the risk of stroke, remains suboptimal.

Address: Cardiology Division, Ospedale Garibaldi-Nesima, Azienda di Rilievo Nazionale e Alta Specializzazione 'Garibaldi' Catania, Italy.; ANMCO Research Center of the Heart Care Foundation, Via La Marmora, 36, Firenze, Italy.; Cardiology Division, San Maurizio Regional Hospital of Bolzano, Bolzano, Italy.; UOC Cardiologia-UTIC, San Filippo Neri Hospital, Rome, Italy.; Division of Cardiology, San Giovanni Evangelista Hospital, Tivoli, Italy.; Cardiovascular Center, Azienda Sanitaria Universitaria Integrata di Trieste, Trieste, Italy.; Cardiology Division, Department of Diagnostics, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy.; Division of Cardiology, Maggiore Hospital, Bologna, Italy.; Unit of Cardiology, S. Spirito Hospital, Casale Monferrato, Italy.; Interventional Cardiology-CCU Department, G. Rummo Hospital, Benevento, Italy.
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