Clinical Application of Enhanced Recovery After Surgery in Perioperative Period of Laparoscopic Colorectal Cancer Surgery.

Qianju Li, Lei Du, Liesheng Lu, Yifeng Tong, Songbo Wu, Yanfei Yang, Qineng Hu, Yukun Wang

Journal: Journal of laparoendoscopic & advanced surgical techniques. Part A 2019;29(2):178-183

PMID: 30614769

Abstract

OBJECTIVE

To investigate the clinical application value of enhanced recovery after surgery (ERAS) combined with the laparoscopic technique in the radical resection of colorectal cancer.

METHODS

A total of 200 patients undergoing laparoscopic radical surgery for colorectal cancer from June 2014 to June 2017 were selected and randomly divided into ERAS group (n = 100) and conventional (CON) group (n = 100). The ERAS group adopted enhanced recovery approach after surgery for perioperative treatment, while the CON group adopted a CON approach. The operation time, blood loss, first exhaust time, first defecation time, extubation time, complication rate (incision infection, pneumonia, gastric retention, anastomotic leakage, intestinal obstruction, etc.), scores of visual analog scale (VAS) 1, 3, and 7 days after surgery, and nutritional status (albumin, total protein) 1, 3, and 7 days after surgery were compared and analyzed.

RESULTS

Compared with the CON group, the ERAS group had significantly shorter first exhaust time, first defecation time, and extubation time (all P < .05). The incidence of overall complications in the ERAS group was less than those in the CON group (P < .05); and albumin and total protein were significantly higher in the ERAS group than in the CON group (both P < .05).

CONCLUSIONS

ERAS combined with laparoscopic techniques for the treatment of colorectal cancer is a safe and feasible practice. It not only promoted the recovery of gastrointestinal function but also improved the perioperative nutritional status of patients.

Address: 1 Department of Gastrointestinal Surgery, Ninghai First Hospital , Ninghai, China .; 2 Department of Metabolic Surgery, Shanghai Tenth People's Hospital , Shanghai City, China .; 3 School of Medicine, Tongji University , Shanghai City, China .

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