Hypoxia attenuates inflammation-induced hepcidin synthesis during experimental human endotoxemia.

Dorien Kiers, Lucas T van Eijk, Johannes G van der Hoeven, Dorine W Swinkels, Peter Pickkers, Matthijs Kox

Journal: Haematologica 2020;104(6):e230-e232

PMID: 30655372

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Abstract

Address: Department of Intensive Care Medicine, Radboud University Medical Center.; Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Medical Center.; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center.; Department of Laboratory Medicine, Translational Metabolic Laboratory, Radboud University Medical Center.; Hepcidinanalysis.com, Nijmegen, the Netherlands.; Department of Intensive Care Medicine, Radboud University Medical Center [email protected].

DOI: 10.3324/haematol.2018.202796

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MeSH Terms: Biomarkers, Disease Susceptibility, Endotoxemia, Hepcidins, Homeostasis, Humans, Hypoxia, Inflammation, Iron, Protein Binding