Multidrug- and colistin-resistant Salmonella enterica 4,[5],12:i:- sequence type 34 carrying the mcr-3.1 gene on the IncHI2 plasmid recovered from a human.

Daniel F Monte, Valerie Nelson, Louise Cerdeira, Shivaramu Keelara, Shermalyn Greene, Denise Griffin, Shadia Rath, Robbie Hall, Nichole Page, Thomas Lawson, Debra Springer, Paula J Fedorka-Cray, Siddhartha Thakur

Journal: Journal of medical microbiology 2019;68(7):986-990

PMID: 31162025

Abstract

A colistin-resistant Salmonella enterica 4, [5],12:i:- sequence type (ST) 34 harbouring mcr-3.1 was recovered from a patient who travelled to China 2 weeks prior to diarrhoea onset. Genomic analysis revealed the presence of the mcr-3.1 gene located in the globally disseminated IncHI2 plasmid, highlighting the intercontinental dissemination of the colistin-resistant S. enterica 4, [5],12:i:- ST34 pandemic clone.

Address: Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Department of Population Health and Pathobiology, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA.; Department of Clinical Analysis, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.; Department of Health and Human Services, Molecular Diagnostic and Epidemiology Laboratory Unit at State Laboratory of Public Health, Division of Public Health, Raleigh, NC, USA.; Comparative Medicine Institute, North Carolina State University, Raleigh, NC, USA.
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