Vitamin D and Otitis Media.

Rebecca E Walker, Jim Bartley, Carlos A Camargo, Edwin A Mitchell

Journal: Current allergy and asthma reports 2020;19(7):33

PMID: 31161313

Abstract

PURPOSE OF REVIEW

To examine the relationship between vitamin D and otitis media.

RECENT FINDINGS

Vitamin D deficiency has been associated with several respiratory diseases, including otitis media. Vitamin D supplementation may reduce the risk of otitis media. This relationship may be explained by vitamin D supporting the immune system by upregulating antimicrobial peptides which are effective against otopathogens and biofilm formation, supporting a less inflammatory immune response, or promoting beneficial commensal bacteria. This review will explore risk factors of both otitis media and vitamin D deficiency, the evidence of vitamin D being beneficial for various forms of otitis media, and possible mechanisms of action.

Address: Department of Paediatrics: Child and Youth Health, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand. [email protected].; Division of Otolaryngology-Head and Neck Surgery, Counties-Manukau District Health Board, Auckland, New Zealand.; Department of Emergency Medicine and Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA.; Department of Paediatrics: Child and Youth Health, The University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.

DOI: 10.1007/s11882-019-0866-2

Link outs

Free resources

Medical:

https://medlineplus.gov/earinfections.html

Research Materials:

https://antibodies.cancer.gov/detail/CPTC-BRIP1-5

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Full Text Sources:

https://dx.doi.org/10.1007/s11882-019-0866-2

MeSH Terms: Dietary Supplements, Humans, Otitis Media, Vitamin D, Vitamin D Deficiency, Vitamins