: A Plant Used in Traditional Medicine and Its Potential for Clinical Uses.

Sonali Aswal, Ankit Kumar, Ruchi Badoni Semwal, Ashutosh Chauhan, Abhimanyu Kumar, Jörg Lehmann, Deepak Kumar Semwal

Journal: Medicina (Kaunas, Lithuania) 2019;55(6):255

PMID: 31181697

Abstract

(Roxb.) Jessop (Asparagaceae) is a reputed Ayurvedic medicine for a number of therapeutic benefits, including for cardiac diseases, indigestion, asthma, dropsy, rheumatism, leprosy, and skin ailments. The present work aimed to critically and extensively review its traditional uses, phytochemistry, pharmacology, toxicology, and taxonomy together with the mechanisms of action of selected extracts of . A systematic literature survey from scientific databases such as PubMed, Scopus, and Web of Science as well as from some textbooks and classical texts was conducted. The plant, mainly its bulb, contains various bioactive constituents, such as alkylresorcinols, bufadienolides, phytosterols, and flavonoids. Various scientific studies have proven that the plant has anthelmintic, anticancer, antidiabetic, antimicrobial, antioxidant, and wound healing activities. The present work concludes that has the potential to treat various diseases, mainly microbial infections. This review also suggests that bufadienolides, flavonoids, and steroids might be responsible for its bioactive potential.

Address: Research and Development Centre, Faculty of Biomedical Sciences, Uttarakhand Ayurved University, Harrawala, Dehradun 248001, India. [email protected].; Research and Development Centre, Faculty of Biomedical Sciences, Uttarakhand Ayurved University, Harrawala, Dehradun 248001, India. [email protected].; Department of Chemistry, Pt. Lalit Mohan Sharma Government Postgraduate College, Rishikesh 249201, Uttarakhand, India. [email protected].; Department of Biotechnology, Faculty of Biomedical Sciences, Uttarakhand Ayurved University, Harrawala, Dehradun 248001, India. [email protected].; Vice Chancellor, Uttarakhand Ayurved University, Harrawala, Dehradun 248001, India. [email protected].; Department of Therapy Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Perlickstr. 1, 04103 Leipzig, Germany. [email protected].; Department of Phytochemistry, Faculty of Biomedical Sciences, Uttarakhand Ayurved University, Harrawala, Dehradun 248001, India. [email protected].

DOI: 10.3390/medicina55060255

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MeSH Terms: Drimia, Humans, Medicine, Traditional, Phytotherapy, Plant Extracts