Oral mucosal changes associated with primary diseases in other body systems.

Sharon Elad, Yehuda Zadik, Jack G Caton, Joel B Epstein

Journal: Periodontology 2000 2019;80(1):28-48

PMID: 31090141

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Abstract

Systemic diseases may manifest in the oral cavity. This chapter reviews the oral mucosal pathology in blood diseases, gastrohepatic diseases, kidney diseases, immunologic and connective tissue diseases, endocrine diseases, pulmonary diseases, nutritional deficiencies, dermatologic diseases, as well as cancer-associated oral mucosal conditions. The oral mucosa is one of the most commonly affected tissues and may present with unique clinical appearances. Oral mucosal involvement may be the first presentation of the systemic disease or reflect activity or progression of the primary condition. Therefore, it is of importance to be familiar with oral mucosal manifestations of these systemic diseases.

Address: Department of Oral Medicine, Eastman Institute for Oral Health, Rochester, New York, USA.; Hospital Dentistry, Strong Memorial Hospital, Rochester, New York, USA.; Oral Medicine for Hematologic and Oncologic Patients, Department of Oral Medicine, Sedation and Maxillofacial Imaging, Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel.; Department of Oral Medicine, Oral and Maxillofacial Institute, Medical Corps, Israel Defense Forces, Tel Hashomer, Israel.; Department of Periodontology, Eastman Institute for Oral Health, Rochester, New York, USA.; Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.; Division of Otolaryngology and Head and Neck Surgery City of Hope, City of Hope National Medical Center, Duarte, California, USA.

DOI: 10.1111/prd.12265

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MeSH Terms: Humans, Mouth Diseases, Mouth Mucosa