Patterns of Gestational Weight Gain and Infants Born Large-for-Gestational Age Across Consecutive Pregnancies.

Elizabeth L Adams, Michele E Marini, Krista S Leonard, Danielle Symons Downs, Ian M Paul, Jennifer L Kraschnewski, Kristen H Kjerulff, Jennifer S Savage

Journal: Women's health issues : official publication of the Jacobs Institute of Women's Health 2019;29(2):194-200

PMID: 30527864

Free Full Text on PubMed Central View on PubMed

Abstract

INTRODUCTION

Factors that occur between consecutive pregnancies may influence repeated excessive gestational weight gain (GWG) and infants born large-for-gestational age (LGA). We examined interpregnancy interval, weight retention, and GWG in women's first pregnancy as predictors of excessive GWG and LGA in women's second pregnancy.

METHODS

We used data from women's first two live births during the First Baby Study, a 3-year prospective observational cohort of first-time mothers (N = 549). GWG was calculated as weight at delivery minus prepregnancy weight for first and second pregnancies and categorized using the Institute of Medicine guidelines. Weight retention at 6 and 12 months and interpregnancy interval (time from first live birth to conception of second infant) were quantified. Infants were considered LGA if birthweight was in the 90th percentile or greater for gestational age.

RESULTS

Many women (51.7%) exceeded GWG recommendations in both pregnancies. Women who exceeded guidelines in their first pregnancy had a 5.08 greater odds (p < .01) for exceeding guidelines in their second pregnancy, compared with women who did not exceed guidelines in their first pregnancy. Interpregnancy interval and weight retention had no association with exceeding guidelines in women's second pregnancy. Exceeding guidelines in women's first pregnancy resulted in a 4.48 greater odds (p < .01) of first-born infants being LGA, and exceeding guidelines in women's second pregnancy resulted in a 1.82 greater odds of second-born infants being large-for-gestational age (p = .02), compared with women who met guidelines in their first or second pregnancy, respectively.

CONCLUSIONS

Exceeding GWG guidelines in women's first pregnancy predicted exceeding guidelines in their second pregnancy, independent of interpregnancy interval and weight retention.

Address: Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania; Center for Childhood Obesity Research, The Pennsylvania State University, University Park, Pennsylvania.; Center for Childhood Obesity Research, The Pennsylvania State University, University Park, Pennsylvania.; Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania.; Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania; Department of Obstetrics and Gynecology, Penn State College of Medicine, Hershey, Pennsylvania.; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania; Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania.; Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania.; Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania; Center for Childhood Obesity Research, The Pennsylvania State University, University Park, Pennsylvania. Electronic address: [email protected].

DOI: 10.1016/j.whi.2018.10.008

Link outs

Free resources

Full Text Sources:

Medical:

https://medlineplus.gov/healthproblemsinpregnancy....

Miscellaneous:

https://assays.cancer.gov/CPTAC-1496

Subscription / membership required

Full Text Sources:

MeSH Terms: Adult, Birth Weight, Body Mass Index, Cohort Studies, Female, Fertilization, Gestational Age, Gestational Weight Gain, Gravidity, Humans, Infant, Infant, Newborn, Live Birth, Mothers, Patient Compliance, Pregnancy, Pregnancy Complications, Prospective Studies, Weight Gain