Bloating and Abdominal Distension: Clinical Approach and Management.

Amir Mari, Fadi Abu Backer, Mahmud Mahamid, Hana Amara, Dan Carter, Doron Boltin, Ram Dickman

Journal: Advances in therapy 2020;36(5):1075-1084

PMID: 30879252

Abstract

Functional abdominal bloating and distension (FABD) are common gastrointestinal complaints, encountered on a daily basis by gastroenterologists and healthcare providers. Functional abdominal bloating is a subjective sensation that is commonly associated with an objective abdominal distension. FABD may be diagnosed as a single entity (the sole or cardinal complaint) or may overlap with other functional gastrointestinal disorders such as functional constipation, irritable bowel syndrome, and functional dyspepsia. The pathophysiology of FABD is not completely understood. Proposed underlying mechanisms include visceral hypersensitivity, behavioral induced abnormal abdominal wall-phrenic reflexes, the effect of poorly absorbed fermentable carbohydrates, and microbiome alterations. Management includes behavioral therapy, dietary interventions, microbiome modulation, and medical therapy. This review presents the current knowledge on the pathophysiology, evaluation, and management of FABD.

Address: Gastroenterology Institute, Hillel Yaffe Medical Center, Hadera, Israel.; Gastroenterology Institute, Nazareth EMMS Hospital, Nazareth, Israel.; Faculty of Medicine in the Galilee, Bar-Ilan University, Ramat Gan, Israel.; Department of Gastroenterology, Chaim Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Division of Gastroenterology, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.; Division of Gastroenterology, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel. [email protected].; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. [email protected].
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