Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma.

Address: Institute of Human Genetics, Ulm University and Ulm University Medical Center, 89081, Ulm, Germany.; Institute of Human Genetics, Christian-Albrechts-University, 24105, Kiel, Germany.; Division of Theoretical Bioinformatics (B080), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Department for Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology and Bioquant, University of Heidelberg, 69120, Heidelberg, Germany.; Hematopathology Section, Christian-Albrechts-University, 24105, Kiel, Germany.; Pediatric Hematology and Oncology, University Hospital Giessen, 35392, Giessen, Germany.; Interdisciplinary Center for Bioinformatics, University of Leipzig, 04107, Leipzig, Germany.; Bioinformatics Group, Department of Computer, University of Leipzig, 04107, Leipzig, Germany.; Transcriptome Bioinformatics, LIFE Research Center for Civilization Diseases, University of Leipzig, 04107, Leipzig, Germany.; Department of Pediatric Immunology, Hematology and Oncology, University Hospital, 69120, Heidelberg, Germany.; German Cancer Research Center (DKFZ), Division of Stem Cells and Cancer, Heidelberg, Germany and Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120, Heidelberg, Germany.; Bioinformatics and Omics Data Analytics (B240), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, 69120, Heidelberg, Germany.; Cell Networks, Bioquant and Biochemistry CenterBiochemie Zentrum Heidelberg (BZH), University of Heidelberg, 69120, Heidelberg, Germany.; Institute for Medical Informatics Statistics and Epidemiology, 04107, Leipzig, Germany.; Genome Biology Unit, EMBL Heidelberg, 69117, Heidelberg, Germany.; Division of Molecular Genetics, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Division of Applied Bioinformatics (G200), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Medical Faculty Heidelberg, Heidelberg University, 69120, Heidelber, Germany.; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, 14195, Berlin, Germany.; Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.; Medical Faculty, Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine-University, 40225, Düsseldorf, Germany.; Senckenberg Institute of Pathology, University of Frankfurt Medical School, 60590, Frankfurt am Main, Germany.; Institute of Pathology, Charité - University Medicine Berlin, 10117, Berlin, Germany.; Institute of Clinical Molecular Biology, Christian-Albrechts-University, 24105, Kiel, Germany.; Institute of Pathology, Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080, Würzburg, Germany.; Pathodiagnostik Berlin, 12099, Berlin, Germany.; Department for Internal Medicine III, Ulm University, 89081, Ulm, Germany.; Institute of Cell Biology (Cancer Research), Medical School, University of Duisburg-Essen, 45147, Essen, Germany.; Institute of Pathology, University of Ulm and University Hospital of Ulm, 89081, Ulm, Germany.; Department of Hematology and Oncology, Georg-August-University of Göttingen, 37075, Göttingen, Germany.; Computational Biology, Leibniz Institute on Ageing-Fritz Lipmann Institut (FLI), 07745, Jena, Germany.; University Hospital Münster - Pediatric Hematology and Oncology, 48149, Münster, Germany.; Division of Theoretical Bioinformatics (B080), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [email protected].; Bioinformatics and Omics Data Analytics (B240), German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. [email protected].; Institute of Human Genetics, Ulm University and Ulm University Medical Center, 89081, Ulm, Germany. [email protected].; Institute of Human Genetics, Christian-Albrechts-University, 24105, Kiel, Germany. [email protected].