Diet and Metabolism in the Evolution of Asthma and Obesity.

Anne E Dixon, Fernando Holguin

Journal: Clinics in chest medicine 2020;40(1):97-106

PMID: 30691720

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Abstract

Obesity is a major risk factor for asthma. This association appears related to altered dietary composition and metabolic factors that can directly affect airway reactivity and airway inflammation. This article discusses how specific changes in the western diet and metabolic changes associated with the obese state affect inflammation and airway reactivity and reviews evidence that interventions targeting weight, dietary components, lifestyle, and metabolism might improve outcomes in asthma.

Address: Division of Pulmonary and Critical Care, University of Vermont, Given D209, 89 Beaumont Avenue, Burlington, VT 05482, USA. Electronic address: [email protected].; Division of Pulmonary and Critical Care, Department of Medicine, University of Colorado, Denver, CO 80045, USA; Allergy & Asthma Clinic, Anschutz 1635 Aurora Court, 6th Floor, Aurora, CO 80045, USA.

DOI: 10.1016/j.ccm.2018.10.007

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MeSH Terms: Asthma, Humans, Obesity