Macronutrient Digestion and Absorption in the Preterm Infant.

Marta Rogido, Ian Griffin

Journal: NeoReviews 2020;20(1):e25-e36

PMID: 31261071

Abstract

The human fetus receives oral nutrition through swallowed amniotic fluid and this makes a significant nutritional contribution to the fetus. Postnatally, macronutrient absorption and digestion appear to function well in the preterm infant. Although pancreatic function is relatively poor, the newborn infant has several mechanisms to overcome this. These include a range of digestive enzymes in human milk, novel digestive enzymes involved in fat and protein digestion that do not appear to be present in the older child or adult, and the presence of a -rich colonic microbiome that may "scavenge" unabsorbed macronutrients and make them available to the infant.

Copyright © 2019 by the American Academy of Pediatrics.

Address: Goryeb Children's Hospital, Morristown, NJ.; Mid-Atlantic Neonatal Associates, Morristown, NJ.; Biomedical Research Institute of New Jersey, Cedar Knolls, NJ.

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